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1

Amino Acids in the Development of Prodrugs

Vale, Nuno, Ferreira, Abigail, Matos, Joana, Fresco, Paula, Gouveia, Maria

Journal:

Year:

2018

Language:

english

File:

PDF, 10.99 MB

english, 2018

2

Immunohistochemical localization of angiotensin II receptor types 1 and 2 in the mesenteric artery from spontaneously hypertensive rats

Carmen Diniz, Sandra Leal, Karen Logan, Carolina Rocha-Pereira, Ana Sofia Soares, Eduardo Rocha, Jorge Gonçalves, Paula Fresco

Journal:

Microscopy Research and Technique

Year:

2007

Language:

english

File:

PDF, 308 KB

english, 2007

3

Immunohistochemical characterization of adenosine receptors in rat aorta and tail arteries

Sandra Leal, Carlos Sá, Jorge Gonçalves, Paula Fresco, Carmen Diniz

Journal:

Microscopy Research and Technique

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

4

Semiautomated computer-assisted image analysis to quantify 3,3′-diaminobenzidine tetrahydrochloride-immunostained small tissues

Sandra Leal, Carmen Diniz, Carlos Sá, Jorge Gonçalves, Ana Sofia Soares, Carolina Rocha-Pereira, Paula Fresco

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

5

Synthesis and in vivo modulatory activity of protein kinase C of xanthone derivatives

Lucı́lia Saraiva, Paula Fresco, Eugénia Pinto, Emı́lia Sousa, Madalena Pinto, Jorge Gonçalves

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 341 KB

english, 2002

6

Inhibition of protein kinase C by synthetic xanthone derivatives

Lucı́lia Saraiva, Paula Fresco, Eugénia Pinto, Emı́lia Sousa, Madalena Pinto, Jorge Gonçalves

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 361 KB

english, 2003

7

REGIONAL DIFFERENCES IN EXTRACELLULAR PURINE DEGRADATION IN THE PROSTATIC AND EPIDIDYMAL PORTIONS OF THE RAT VAS DEFERENS

Carmen Diniz, Paula Fresco, Jorge Gonçalves

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2005

Language:

english

File:

PDF, 233 KB

english, 2005

8

Release inhibitory receptors activation favours the A2A-adenosine receptor-mediated facilitation of noradrenaline release in isolated rat tail artery

Paula Fresco, Carmen Diniz, Glória Queiroz, Jorge Gonçalves

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

9

Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay

Lucı́lia Saraiva, Paula Fresco, Eugénia Pinto, Jorge Gonçalves

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 543 KB

english, 2004

10

Adenosine receptors involved in modulation of noradrenaline release in isolated rat tail artery

Carmen Diniz, Paula Fresco, Sandra Leal, Jorge Gonçalves

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

11

Chromium(VI)-mediated DNA damage: oxidative pathways resulting in the formation of DNA breaks and abasic sites

Montserrat Casadevall, Paula da Cruz Fresco, Andreas Kortenkamp

Journal:

Chemico-Biological Interactions

Year:

1999

Language:

english

File:

PDF, 147 KB

english, 1999

12

Taurine release in the rat vas deferens is modulated by Ca2+ and is independent of contractions

Carmen Diniz, Paula da Cruz Fresco, Jorge Gonçalves

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

13

A2A adenosine-receptor-mediated facilitation of noradrenaline release in rat tail artery involves protein kinase C activation and βγ subunits formed after α2-adrenoceptor activation

Paula Fresco, Jorge M.A. Oliveira, Filip Kunc, Ana Sofia Soares, Carolina Rocha-Pereira, Jorge Gonçalves, Carmen Diniz

Journal:

Neurochemistry International

Year:

2007

Language:

english

File:

PDF, 417 KB

english, 2007

14

An intermediate form of NADP-malic enzyme from the C3 C4 intermediate species Flaveria floridana

Paula Casati, Analia G Fresco, Carlos S. Andreo, Marı́a F. Drincovich

Journal:

Year:

1999

Language:

english

File:

PDF, 134 KB

english, 1999

15

Online drug databases: a new method to assess and compare inclusion of clinically relevant information

Cristina Silva, Paula Fresco…

Journal:

International Journal of Clinical Pharmacy

Year:

2013

Language:

english

File:

PDF, 2.13 MB

english, 2013

16

Potentiation of cytotoxicity of paclitaxel in combination with Cl-IB-MECA in human C32 metastatic melanoma cells: A new possible therapeutic strategy for melanoma

Soares, Ana S., Costa, Vera M., Diniz, Carmen, Fresco, Paula

Journal:

Biomedicine & Pharmacotherapy

Year:

2013

Language:

english

File:

PDF, 1.75 MB

english, 2013

17

The Reductive Conversion of Chromium(VI) by Ascorbate Gives Rise to Apurinic/Apyrimidinic Sites in Isolated DNA

Fresco, Paula da Cruz, Shacker, Fatemeh, Kortenkamp, Andreas

Journal:

Chemical Research in Toxicology

Year:

1995

Language:

english

File:

PDF, 964 KB

english, 1995

18

Inosine Strongly Enhances Proliferation of Human C32 Melanoma Cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K Pathways

Soares, Ana Sofia, Costa, Vera Marisa, Diniz, Carmen, Fresco, Paula

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2015

Language:

english

File:

PDF, 579 KB

english, 2015

19

The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma

Soares, Ana S., Costa, Vera M., Diniz, Carmen, Fresco, Paula

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 684 KB

english, 2014

20

Biologically relevant O,S-donor compounds. Synthesis, molybdenum complexation and xanthine oxidase inhibition

Chaves, Sílvia, Gil, Marco, Canário, Sónia, Jelic, Ratomir, Romão, Maria João, Trincão, José, Herdtweck, Eberhardt, Sousa, Joana, Diniz, Carmen, Fresco, Paula, Santos, M. Amélia

Journal:

Dalton Transactions

Year:

2008

Language:

english

File:

PDF, 354 KB

english, 2008

21

Isoform-selectivity of PKC Inhibitors Acting at the Regulatory and Catalytic Domain of Mammalian PKC-α, -βI, -δ, -η and -ζ

Saraiva, Lucília, Fresco, Paula, Pinto, Eugénia, Gonçalves, Jorge

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 283 KB

english, 2003

22

Endothelial dysfunction impairs vascular neurotransmission in tail arteries

Sousa, Joana B., Fresco, Paula, Diniz, Carmen

Journal:

Neurochemistry International

Year:

2015

Language:

english

File:

PDF, 763 KB

english, 2015

23

Drug-related problems in institutionalized, polymedicated elderly patients: opportunities for pharmacist intervention

Silva, Cristina, Ramalho, Célia, Luz, Isabel, Monteiro, Joaquim, Fresco, Paula

Journal:

International Journal of Clinical Pharmacy

Year:

2015

Language:

english

File:

PDF, 221 KB

english, 2015

24

The formation of DNA cleaving species during the reduction of chromate by ascorbate

da Cruz Fresco, Paula, Kortenkamp, Andreas

Journal:

Year:

1994

Language:

english

File:

PDF, 990 KB

english, 1994

25

Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives

M. Marques, M. Paula, Borges, Fernanda, Sousa, Joana, Calheiros, Rita, Garrido, Jorge, Gaspar, Alexandra, Diniz, Carmen, Fresco, Paula

Journal:

Letters in Drug Design & Discovery

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

26

Characterization of pharmacy services in Portuguese prisons: a national survey

Alexandra Monteiro Guerra, Liliana, Façanha da Cruz Fresco, Paula

Journal:

International Journal of Prisoner Health

Year:

2013

Language:

english

File:

PDF, 250 KB

english, 2013

27

Differential Activation by Daphnetoxin and Mezerein of PKC-Isotypes α, βI, δ and ζ

Saraiva, Lucília, Fresco, Paula, Pinto, Eugénia, Portugal, Helena, Gonçalves, Jorge

Journal:

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

28

Differential Activation of Protein Kinase C Isoforms by Euxanthone, Revealed by an In Vivo Yeast Phenotypic Assay

Saraiva, Lucília, Fresco, Paula, Pinto, Eugénia, Kijjoa, Anake, Gonzalez, Maria José, Gonçalves, Jorge

Journal:

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

29

Inhibition of α, βI, δ, η and ζ Protein Kinase C Isoforms by Xanthonolignoids

Saraiva, Lucília, Fresco, Paula, Pinto, Eugénia, Sousa, Emília, Pinto, Madalena, Gonçalves, Jorge

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 772 KB

english, 2003

30

Evidence of Different Propofol Pharmacokinetics under Short and Prolonged Infusion Times in Rabbits

Campos, Sónia, Monteiro, Joaquim, Valenzuela, Belén, Gonçalinho, Helena, de Pinho, Paula Guedes, Fresco, Paula, Félix, Luis, Antunes, Luís

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2016

Language:

english

File:

PDF, 294 KB

english, 2016

31

Impaired Inhibitory Function of Presynaptic A1-Adenosine Receptors in SHR Mesenteric Arteries

Rocha-Pereira, Carolina, Magdalena Arribas, Silvia, Fresco, Paula, Carmen González, Maria, Gonçalves, Jorge, Diniz, Carmen

Journal:

Journal of Pharmacological Sciences

Year:

2013

Language:

english

File:

PDF, 6.75 MB

english, 2013

32

Endothelial and Neuronal Nitric Oxide Activate Distinct Pathways on Sympathetic Neurotransmission in Rat Tail and Mesenteric Arteries

Sousa, Joana Beatriz, Vieira-Rocha, Maria Sofia, Arribas, Silvia M., González, Maria Carmen, Fresco, Paula, Diniz, Carmen, Mongin, Alexander A.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

33

Medication Adherence Measures: An Overview

Lam, Wai Yin, Fresco, Paula

Journal:

BioMed Research International

Year:

2015

Language:

english

File:

PDF, 1.26 MB

english, 2015

34

Adenosine Receptor Ligands on Cancer Therapy: A Review of Patent Literature

Sousa, Joana B., Fresco, Paula, Diniz, Carmen, Goncalves, Jorge

Journal:

Recent Patents on Anti-Cancer Drug Discovery

Year:

2018

Language:

english

File:

PDF, 2.62 MB

english, 2018

35

Vancomycin therapeutic drug monitoring and population pharmacokinetic models in special patient subpopulations

Monteiro, Joaquim F., Hahn, Siomara R., Gonçalves, Jorge, Fresco, Paula

Journal:

Pharmacology Research & Perspectives

Year:

2018

Language:

english

File:

PDF, 2.43 MB

english, 2018

36

Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite

Duarte, Diana, Amaro, Filipa, Silva, Isabel, Silva, Dany, Fresco, Paula, Oliveira, José C., Reguengo, Henrique, Gonçalves, Jorge, Vale, Nuno

Journal:

Year:

2019

Language:

english

File:

PDF, 2.92 MB

english, 2019

37

Î²-Adrenoceptor Activation in Breast MCF-10A Cells Induces a Pattern of Catecholamine Production Similar to that of Tumorigenic MCF-7 Cells

Amaro, Filipa, Silva, Dany, Reguengo, Henrique, Oliveira, JosÃ© C., Quintas, Clara, Vale, Nuno, GonÃ§alves, Jorge, Fresco, Paula

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 1.24 MB

2020

38

Intracellular adenosine released from THP-1 differentiated human macrophages is involved in an autocrine control of Leishmania parasitic burden, mediated by adenosine A2A and A2B receptors

Silva, Dany, Moreira, Diana, Cordeiro-da-Silva, Anabela, Quintas, Clara, GonÃ§alves, Jorge, Fresco, Paula

Journal:

European Journal of Pharmacology

Year:

2020

File:

PDF, 244 KB

2020

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